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Clinical data
Pronunciation/ eɪ ˈ s aɪ k l oʊ v ɪər /
Trade namesZovirax, others [1]
License dataUS   FDA: Acyclovir
Pregnancy categoryAU: B3 US: B (No risk in non-human studies)
Routes of administrationIntravenous, by mouth, topical (including eye ointment)
ATC codeJ05AB01 ( WHO ) D06BB03 ( WHO ) S01AD03 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) for tablet and injection. Unscheduled for cream form under 10 g., CA : ℞-only UK: POM (Prescription only) for tablet and injection. GSL (OTC) for cream form under 2 g., US: ℞-only
Pharmacokinetic data
Bioavailability15–20% (by mouth) [2]
Protein binding9–33% [2]
Elimination half-life2–4 hours
ExcretionKidney (62–90% as unchanged drug)

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Mcg/mL, respectively, and mean steady-state trough serum concentrations of. 2. Pharmacist Dispensing Of Opioid Prescriptions: Issues ... FIRST EPISODE: zovirax 3 unguento oftalmico g orally twice a day for 7 to 10 days CDC recommendation RECURRENT EPISODES: 1 g orally twice a day for 5 to 10 days CDC recommendation All patients with newly acquired genital herpes should receive antiviral therapy as first episodes can cause a prolonged clinical illness, even among persons with mild clinical manifestations initially.

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Store at room temperature between 15 and 30 degrees C 59 and 86 degrees F Throw away any unused medicine after the expiration date.microgram/ml The pharmacokinetics of aciclovir in children over one year zovirax 3 unguento oftalmico seem to be similar to those of adults. reatment of herpes simplex virus HSV infections of the skin and mucous membranes including initial and recurrent genital herpes excluding neonatal HSV and severe HSV infections in immunocompromised children Prevention of herpes simplex virus infections in immunocompromised patients.

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McCormick DP. Herpes-simplex virus as a cause of Bell's palsy.Teratogenic Effects: Pregnancy Category B. Acyclovir administered during organogenesis was not teratogenic in the mouse 450 mg/kg/day, p. rabbit 50 mg/kg/day, s.

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It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: hra.Suppression of herpes simplex infections in immunocompetent patients: 200 mg Aciclovir should be taken four times daily at approximately six-hourly intervals. Many patients may be conveniently managed on a regimen of 400 mg Zovirax 3 unguento oftalmico twice daily at approximately twelve-hourly intervals.

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Plasma acyclovir concentrations were below the acyclovir following topical application of cream has not been evaluated in cell culture and in vivo inhibitory activity against HSV types 1 HSV-1 and zovirax unguento oftalmico to its affinity for the enzyme thymidine kinase TK encoded by HSV. This viral enzyme converts acyclovir into acyclovir monophosphate, a nucleotide analogue.1 In all zovirax unguento oftalmico the studies in which acyclovir treatment was patient initiated, the mean lesion healing time was reduced by approximately 1 to 2 days compared with placebo.

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And 0.This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: hra.

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