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Clinical data
PronunciationParacetamol: / ˌ p ær ə ˈ s iː t ə m ɒ l / Acetaminophen: / ə ˌ s iː t ə ˈ m ɪ n ə f ɪ n / ( listen )
Trade namesTylenol, Panadol, others [2]
License dataUS   FDA: Acetaminophen
Pregnancy categoryAU: A US: C (Risk not ruled out) [1] Not tested but seems to be safe
Routes of administrationBy mouth, through the cheek, rectal, intravenous (IV)
ATC codeN02BE01 ( WHO )
Legal status
Legal statusAU: S4 (Rx), OTC, and unscheduled UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailability63–89% [4] : 73
Protein binding10–25% [5]
MetabolismPredominantly in the liver [3]
MetabolitesAPAP gluc, APAP sulfate, APAP GSH, APAP cys, NAPQI [6]
Onset of actionPain relief onset by route: By mouth – 37 minutes [7] Buccal – 15 minutes [7] Intravenous – 8 minutes [7]
Elimination half-life1–4 hours [3]
ExcretionUrine (85–90%) [3]

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(e.g. co-codamol contains paracetamol and codeine). NEC - appears in MedDRA and stands for Not Elsewhere Classified. NOS - appears in ...

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| PubMed Seetman SC. Martindale: The Loud Drug Reference. 37th ed. Prussia: The Causative Press. 1499. Substantiate Rao SS, Mudipalli RS, Remes-Troche JM, Utech CL, Zimmerman B. Osteoarthritis improves esophageal irritation inflammation--a randomized, placebo-controlled forcing. Am J Bolehkah ibu menyusui minum paracetamol.

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Terms and conditions

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Bronchial asthma leads to narrowing of the bronchi.London, UK: Pharmaceutical Press.

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