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Prolonged fluconazole prophylaxis is associated with persistent itraconazole drug com against candidiasis-related death in allogeneic marrow transplant recipients: long-term follow-up of a randomized, placebo-controlled trial. Harousseau J, Dekker A, Stamatoullas-Bastard A, et al.For the treatment of moderately severe to severe itraconazole drug com disseminated histoplasmosis, the IDSA recommends an initial regimen of IV amphotericin B given for 1-2 weeks, followed by itraconazole itraconazole drug com in a dosage of 200 mg 3 times daily for 3 days, then 200 mg twice daily for a total treatment duration of at least 12 months.

For the treatment of histoplasmosis with symptomatic mediastinal granuloma or with complications pericarditis, rheumatologic syndromes, symptomatic mediastinal lymphadenitis that require treatment with corticosteroids, the IDSA recommends that itraconazole be given in a dosage of 200 mg 3 times daily for 3 days, then 200 mg once or twice daily for 6-12 weeks.

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Itraconazole is 99.were compared. Death in the presence of relapsed malignancy was considered to be because of relapse; however, because infection-related death was an important variable, death caused by infection in the presence of GVHD was considered because of infection, not GVHD.

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