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This medicine is to be erectile dysfunction drugs and nitroglycerin only by or under the direct supervision of your doctor. Copyright 2020 IBM Watson Health.It works to relax the muscles around the anus so there is less pressure in the area.
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1-2 spra s PRN for angina, may repeat q3-5min, not to exceed 3 nitroglycerins and erectile dysfunction medications in 15 minutes Spray onto or under tongue; do not inhale, expectorate or rinse mouth for 5-10 minutes Seek medical attention if pain persists after 3 doses in 15 minutes 1-2 sprays 5-10 minutes before activities likely to cause angina CrCl: 10-50 mg/min: Administer q24-72hr CrClAngina1-2 spra s PRN for angina, may repeat q3-5min, not to exceed 3 sprays in 15 minutes Spray onto or under tongue; do not inhale, expectorate or rinse mouth for 5-10 minutes Seek medical attention if pain persists after 3 doses in 15 minutes 1-2 sprays 5-10 minutes before activities likely to cause anginaHeadache Hypotension Tachycardia Dizziness Lightheadedness Blurred vision Flushing N/V Nervousness Xerostomia Methemoglobinemia rare Syncope Prolonged bleeding time Exfoliative dermatitis Unstable angina Rebound hypertension Thrombocytopenia Hypersensitivity AMI, severe anemia Recent use within several days of PDE-5 inhibitors eg, avanafil, sildenafil, tadalafil, or vardenafil may nitroglycerin and erectile dysfunction medications dangerously low hypotension; the time course of the interaction appears to be related to the PDE-5 inhibitor half-life Soluble guanylate cyclase sGC stimulator, riociguat; coadministration may cause hypotension Narrow angle glaucoma controversial: may not be clinically significant Increased intracranial pressure Circulatory failure or shock CHF, alcohol use, glaucoma, hyperthyroidism, hypertrophic cardiomyopathy, increased ICP eg, head trauma, cerebral hemorrhage; potential contraindication increased IOP, postural hypotension, volume depletion, low systolic BP Severe hypotension may occur with small doses especially in patients with constrictive pericarditis, aortic or mitral stenosis, volume depleted patients or that are already nitroglycerin and erectile dysfunction medications hypotension may be accompanied by paradoxical bradycardia and/or increased angina pectoris Do not change brands unintentionally as not all are bioequivalent Treat drug-induced headache nitroglycerin and erectile dysfunction medications aspirin or acetaminophen Provide nitrate-free interval 10-12 hr or overnight to avoid development of tolerance; excessive use my lead to development of tolerance Inability to relieve chest pain after 3 doses may mean AMI-rush to ER if nitroglycerin and erectile dysfunction medications Discontinue if blurred vision develops Prime pump prior to first use or after prolonged nonuse Use supportive treatment in overdose May aggravate the angina caused by hypertrophic obstructive cardiomyopathy Nitroglycerin produces dose-related headaches, especially at the start of nitroglycerin therapy, which may be severe and persistent but usually subside with continued use Dose selection for elderly should start at low end of dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy Pregnancy Category: C Lactation: resource known whether drug crosses into breast milk, use cautionA: Generally acceptable.
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PHARMACIST: Dispense the accompanying Patient Information to each patient. PHARMACIST: Dispense the accompanying Patient Information to each patient.L/kg. At plasma concentrations between 50 and 500 ng/mL, the binding of nitroglycerin to plasma proteins is approximately 60% while that of 1, - and 1, -dinitroglycerin is 60% and 30% respectively.
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