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Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at a greater risk for serious GI events.This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: hra.

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Experimental data suggest that ibuprofen may competitively inhibit the effect of low dose aspirin acetylsalicylic acid on platelet aggregation when they are dosed concomitantly.ntihypertensives and diuretics: since NSAIDs may diminish the effects of these drugs. In some patients with compromised renal function e.

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In some patients with compromised renal function e. dehydrated patients or elderly patients with compromised renal function the co-administration of an ACE inhibitor or Angiotensin II antagonist and agents that inhibit cyclo-oxygenase may result in further deterioration of renal function, including possible acute renal failure, which is usually reversible.Always read the label.

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There is a risk of kidney problems in dehydrated children and adolescents.There is a risk of renal impairment in dehydrated children and adolescents Caution discussion with doctor or pharmacist is required prior to starting treatment in patients with a history of hypertension and/or heart failure as fluid retention, hypertension and oedema have been how many nurofen plus can i take in association with NSAID therapy.

Clinical studies suggest that use of ibuprofen, particularly at a high dose 2400mg/day may be associated with a small increased risk of arterial thrombotic events for example myocardial infarction or stroke Overall, epidemiological studies do not suggest that low dose ibuprofen e.

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