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Cabergoline
Clinical data
Trade namesCabaser, Dostinex
AHFS/Drugs.comMonograph
License dataUS   FDA: CABERGOLINE
Pregnancy categoryUS: B (No risk in non-human studies)
Routes of administrationOral
ATC codeG02CB03 ( WHO ) N04BC06 ( WHO )
Legal status
Legal statusUS: ℞-only
Pharmacokinetic data
BioavailabilityFirst-pass effect seen; absolute bioavailability unknown
Protein bindingModerately bound (40–42%); concentration-independent
MetabolismHepatic, predominately via hydrolysis of the acylurea bond or the urea moiety
Elimination half-life63–69 hours (estimated)
ExcretionUrine (22%), feces (60%)

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